Yes they can actually. Not all will do it though. And sometimes it is pure psychic energy that makes it happen.
The best way to utilise the tickling is to test out your guides to help recognise them. For instance you may be sitting in the power or just meditating and you begin to feel a tickle. You may ask your guide if it is they who are responsible.
You have to set out a good test of recognition such as saying to the guide ‘if it is you will you stop’. If the tickling than ceases then you can assume it is the guide. If it continues it is probably just psychic energy which has built up.
When you are working psychically or mediumistically and you get a tickle on your nose or hair etc you can say is that you….? If it stops then it is most likely that your assumption is correct.
It is though a very usual occurrence whilst building up spirit energy.